Zestoretic Oral : Uses, Side Effects, Interactions


GENERIC NAME(S): Lisinopril-Hydrochlorothiazide


Zestoretic is used to treat high blood pressure. Reducing hypertension helps in preventing stroke, heart attack and kidney problems. This product includes two drugs: Lisinopril and Hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by giving rest to the blood vessels so that the blood flows more easily. Hydrochlorothiazide is a “water table” (diuretic) which causes you to make more urine, which helps your body get rid of excess salt and water.

This product is used when a drug is not controlling your blood pressure. Your doctor can direct you to take personal medicines first, and then you can switch to this combination product. Do not continue to take personal medicines (Lisinopril and / or Hydrochlorothiazide) after starting this drug.

How To Use Zestoretic

If you start taking Zestoretic and you get refills every time, before you are available from your pharmacist, please read the Patient Information Letter. If you have any questions, ask your doctor or pharmacist.

Take this medicine with or without mouth directed by your doctor, usually once in the morning. If this medicine causes you to urinate more frequently, it is best to take it at least 4 hours before your sleeping so that you can get ready to urinate.

If you consume some medicines to reduce your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), then take these medicines at least 4 hours before or at least 4 to 6 hours prior to taking Lisinopril / Hydrochlorothiazide. .

Dosage is based on your medical condition and treatment response.

Use Zestoretic regularly to get the most benefit. To help you remember, take it at the same time every day. Keep taking this medication even if you feel OK. Most people with high blood pressure do not feel sick.

Tell your doctor if your condition is not better or if it gets worse (for example, your blood pressure reading is high or increased).

Side Effects

Dizziness, laziness, fatigue or headache can occur because your body gets adjusted with the drug. Dry cough may also occur. If any of these effects gets worse or worse, then tell your doctor or pharmacist immediately.

To reduce the risk of dizziness and lighthouse, slowly rise while sitting or lying down from the position of lying.

Remember that your doctor has prescribed this drug because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if you have any serious side effects, including: unconsciousness, symptoms of high potassium blood level (such as muscular weakness, slow / irregular heart beat), signs of kidney problems (such as urine volume Change), decrease in vision, eye pain.

Zestoretic can cause excess water (dehydration) and salt / minerals of the body. Tell your doctor immediately if you have any symptoms of dehydration or mineral loss, including: excessive thirst, very dry mouth, muscle spasms / weakness, fast / slow / irregular heartbeat, confusion.

Zestoretic can rarely cause serious (potentially fatal) liver problems. If you have any symptoms of liver deterioration, get medical help, such as: nausea / vomiting that does not stop, loss of appetite, stomach / stomach ache, yellowing of eyes / black skin

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Zestoretic, tell your doctor or pharmacist whether you are allergic to lisinopril or hydrochlorothiazide; Or other ACE inhibitors (such as captoprilbenazepril); Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.

Before using Zestoretic, tell your doctor or pharmacist your medical history, in particular: the history of an allergic reaction in which the swelling of the face / lips / tongue / throat (angioedema), the process of filtering the blood (such as LDL apheresis, dialysis). Bee / wasp sting allergens, gout, lupus, kidney disease, liver disease, desensitizing treatment for skin cancer.

This medication can make you dizzy. Alcohol or marijuana (cannabis) can make you feel more dizzy. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Risk can increase for severe damage to lighthouse or body water (dehydration) in the form of severe sweating, diarrhea, or vomiting. Give long-term diarrhea or vomiting report to your doctor. To prevent dehydration, drink lots of fluids unless your doctor directs you otherwise.

If you have diabetes, this product may affect your blood glucose. Regularly check your blood glucose as directed and share the result with your doctor. Your doctor may need to adjust your diabetes medication, exercise program or diet.

This medicine can make you more sensitive to the sun. It can also increase your risk for skin cancer, especially if you take it for a long time. Keep your time limited in the sun. Avoid Tanning Booths and Sunlamps. Use sunscreen on the outside and wear protective clothing. Tell your doctor immediately if you have sunburn, have blisters / redness in the skin, or notice new or changed moles / skin lesions.

This product can affect your potassium level. Consult your doctor or pharmacist before potassium supplements or potassium before using the option of salt.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

Older adults may be more susceptible to the side effects of this drug, especially in the amount of dizziness and urine (renal problems).

Due to the risk of harm to an unborn child, this drug is not recommended for use during pregnancy. Consult your doctor for more details. (See also the warning section.)

It is unknown if lisinopril passes through breast milk. Hydrochlorothiazide passes through breast milk, but there is no possibility of harming a nursing infant. Consult your doctor before breastfeeding.

Over Dose

If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, unconsciousness


Do not share this medication with others.

Changes in lifestyle that can help this drug work better include exercising, smoking and eating low cholesterol / low fat diet. Consult your doctor for more details.

Labs and / or medical tests (such as kidney function, potassium level) should be done when you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

While taking this medicine, check your blood pressure and pulse (heart rate) regularly. Learn how to check your own blood pressure and pulse at home, and share the results with your doctor.

Missed Dose

If you miss a dose, then as soon as you remember, take it. If it is near the next dose time, then leave the thesis dose. Take your next dose at regular times. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed not to do so, do not flush the medicines in the toilet and do not drain in the drain. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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