Sertraline Oral : Uses, Side Effects, Interactions

Sertraline HCL


GENERIC NAME(S): Sertraline


Sertraline, sold under the trade name Zoloft among others. Sertraline Hcl is used to treat severe forms of depression, panic attacks, obsessive compulsive disorder, traumatic stress disorder, social anxiety disorder (social phobia), and premenstrual syndrome (premenstrual disorder disorder).

Sertraline Hcl can improve your mood, sleep, hunger and energy levels and help you restore your interest in daily life. It can reduce the number of attacks of fear, anxiety, unwanted thoughts and panic attacks. It can reduce the urgency to reduce repeating tasks (compulsions such as handling, counting and checking) that interfere with daily life. Sertraline Hcl is known as a selective serotonin reuptake inhibitor (SSRI). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain.

How To Use Sertraline Hcl

Read the medication guide and, if available, the patient information sheet is provided by your pharmacist before you start using the Sertraline and every time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medicine guided by your doctor, usually once in the morning or even in the evening. The tablet form of this medicine can be taken with or without food. The capsule form is usually taken after breakfast or after the evening meal.

If you are taking Sertraline for premenstrual issues, then your doctor may take you to this medicine every day of the month or for only 2 weeks before your period starts.

Dosage is based on your medical condition and treatment response. To reduce your risk of side effects, your doctor may direct you to start this medication on low dose and gradually increase your dose. Follow your doctor’s instructions carefully. Take this medication regularly to get the most benefit of this. To help you remember, take it every day at the same time.

It is important to continue Sertraline, even if you feel OK. Do not stop taking this medicine without consulting your doctor. When this medicine suddenly stops, some conditions may get worse. In addition, you may experience symptoms such as mood swings, headache, fatigue, changes in sleep, and short feelings similar to electric shock. You may need to reduce your dose gradually to reduce side effects. Report any new or deteriorating symptoms instantly.

Tell your doctor if your condition persists or worsens.

Side Effects

See also the warning section.

Nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, stomach upset or sleepiness may be a problem. If any of these effects persists or worsens, tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed this drug because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if any of these have potential but serious side effects: easy injury / bleeding, decreased interest in sex, decrease in sexual capacity (delay in ejaculation), muscle cramps / weakness, shaking (tremors), abnormal Weight loss

If these rare but serious illnesses / bloody squads, vomiting, coffee grounds, eye pain / swelling / redness, wide pupil, changes in vision (such as looking at the light at night, looking like a blurred vision) Get kind of medical help.

Sertraline can increase serotonin and rarely cause a very serious condition, which is called serotonin syndrome / toxicity. The risk increases if you are taking other medicines that increase the serotonin, so tell your doctor or pharmacist about all the medicines that you take (see the Drug Interactions section). Get medical help immediately when some of the following symptoms develop: Fast heartbeats, hallucinations, loss of coordination, severe dizziness, severe nausea / vomiting / diarrhea, muscle shaking, unexplained fever, abnormal movement or restlessness

Rarely, men may have painful or longer build for 4 or more hours. If this happens, stop using this medicine and get immediate medical assistance, or there may be permanent problems.

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, shortness of breath

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Sertraline, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.

Before using this drug, tell your doctor or pharmacist your medical history, in particular: personal or family history of bipolar / manic-depressive disorder, problem of bleeding, liver disease, seizure disorder, thyroid disease, glucose personal Or family history (angle) method of closing).

Sertraline may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or deaf. Unless you can safely do this, do not drive, use machinery, or do anything that requires caution. Avoid alcoholic beverages. If you are using marijuana, talk to your doctor.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

Older adults may be more susceptible to the side effects of this drug, especially bleeding, or loss of coordination. In older adults, there may be a possibility of developing a type of salt imbalance (hyponatremia), especially if they are taking “water pills” (diuretics). The risk of falling from the loss of coordination can increase.

Children may be more susceptible to the side effects of medicine, especially lowering appetite and losing weight. Monitor weight and height in children taking this drug.

During pregnancy, Sertraline should be used only when explicitly necessary. It can harm an unborn child. In addition, mothers who have used this drug during the last 3 months of pregnancy, children born in them may rarely develop symptoms of withdrawal such as feeding / difficulty breathing, visits, muscles Cramping or crying constantly If you see any of these symptoms in your newborn, then tell the doctor immediately.

Since untreated mental / mood disorders (such as depression, panic attack, obsessive compulsive disorder, post-traumatic stress disorder) can be a serious condition, do not stop taking this medicine until your doctor prescribes it. If you are planning a pregnancy, become pregnant, or think that you may be pregnant, discuss the benefits and risks of using your doctor immediately during pregnancy.

Sertraline passes into breast milk. Consult your doctor before breastfeeding.


Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some products that can interact with this drug include: pimozide, other medicines which can cause bleeding / bruising (antiplatelet drugs such as clopidogrel, NSAID, such as ibuprofen, “blood thinner,” such as warfarin).

Taking the MAO inhibitor with this drug can be a cause of serious (potentially fatal) drug interactions. During treatment with this drug, avoid taking the MAO inhibitor (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most MAO inhibitors should not be taken for two weeks before and after treatment with this drug. Ask your doctor about when to start or stop this medication.

If you are taking other medicines that increase serotonin then the risk of serotonin syndrome / toxicity increases. Examples include Street Drugs, including MDMA / “Bliss,” St. John’s Plant, some antidepressants (such as fluoxetine / paroxetine, SNRI, duloxitine (venlafaxine), tryptophan, others). The risk of serotonin syndrome / toxicity can be high when you start or increase the dose of these medicines.

Tell your doctor or pharmacist whether you are taking other products including alcohol, marijuana, antihistamines (such as cetirizinediphenhydramine), sleeping or anxiety medicines (such as alprazolam, diazepam, zolpidem), muscle relaxants, and alcoholic painkillers Are there. (Such as codeine). Check the label on all your drugs (like allergy or cough-and-cold products), because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Aspirin can increase the risk of bleeding when used with this drug. However, if your doctor has instructed you to take low-dose aspirin for heart attack or stroke prevention (usually on a diet of 81-325 mg in a day), then you should continue it until That your doctor will not instruct you.

Sertraline can interfere with some medical / laboratory tests (including brain scans for Parkinson’s disease), potentially incorrect examination results. Ensure that the lab staff and all your doctors know that you use this medicine.

Over Dose

If someone is treated and has serious symptoms such as difficulty in getting out or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, unconsciousness


Do not share this medication with others.

Keep all regular medical and psychiatric appointments.

Missed Dose

If you miss a dose, then as soon as you remember it, take it. If it is near the next dose time, then leave the thesis dose and set your normal dose. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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