Bamlanivimab and Etesevimab Injection-Uses-Side-Effects-Dosage-Interactions-Reviews
What is the purpose of this medication?
Bamlanivimab and etesevimab injection is used to treat mild to moderate COVID-19 symptoms in certain non-hospitalized adults, children, and infants, including newborns, who have certain medical conditions that put them at higher risk of developing severe COVID-19 symptoms, including hospitalisation or death.
to prevent COVID-19 in people who have not been fully vaccinated against COVID-19 or who have been vaccinated but have a weakened immune system or are taking an immune-suppressing medication and have had close contact or are at high risk of having close contact with someone infected with the SARS-CoV-2 virus (for example, nursing homes, prisons).
Bamlanivimab and etesevimab are also used to treat mild to moderate COVID-19 symptoms in hospitalised children and babies under the age of two, including newborns.
Bamlanivimab and Etesevimab Injection-Uses-Side-Effects-Dosage-Interactions-Reviews
Monoclonal antibodies include bamlanivimab and etesevimab. These drugs operate by preventing the transmission of the virus by inhibiting the function of a natural substance in the body.
How should this medication be administered?
Bamlanivimab and etesevimab injection are available as solutions (liquids) that must be combined with extra liquid before being injected slowly into a vein by a doctor or nurse.
It is given jointly as a one-time dosage as soon as feasible after a positive COVID-19 test and within 10 days after the onset of COVID-19 infection symptoms such as fever, cough, or shortness of breath.
For the prevention of COVID-19 after exposure to someone who is infected with the SARS-CoV-2 virus, bamlanivimab and etesevimab injection should be given as soon as possible after the exposure.
During and after the infusion of bamlanivimab and etesevimab, significant or life-threatening events may occur. A doctor or nurse will closely supervise you while you are getting these drugs and for at least 1 hour thereafter. If you have any of the following symptoms during or after the infusion, contact your doctor or nurse right away: fever, difficulty breathing, chills, fatigue, chest pain, chest discomfort, weakness, confusion, nausea, headache, shortness of breath, wheezing, throat irritation, rash, hives, itching, flushing, muscle pain or dizziness, especially when standing up, sweating, or swelling of the face, throat, tongue, lips, or eyes. If you encounter any of these adverse effects, your doctor may need to scale down or stop your therapy.
Request a copy of the manufacturer’s information for the patient from your chemist or doctor.
Other use for this medication
This drug may also be recommended for other purposes; consult your doctor or chemist for additional details.
What further measures should I take?
Tell your doctor and chemist if you are allergic to bamlanivimab, etesevimab, any other prescriptions, or any of the chemicals in bamlanivimab and etesevimab injection before obtaining it. Request a list of the components from your chemist.
Inform your doctor and chemist about any additional prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal items you are now taking or intend to use. Make sure you include any of the following: cyclosporine (Gengraf, Neoral, Sandimmune), prednisone, and tacrolimus (Astagraf, Envarsus, Prograf). Your doctor may need to adjust the dosage of your drugs or closely monitor you for adverse effects.
Inform your doctor if you have gotten a COVID-19 vaccination or if you have any medical issues now or in the past.
Inform your doctor if you are pregnant, want to become pregnant, or are nursing. Call your doctor if you become pregnant while having bamlanivimab or etesevimab injections.
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What dietary restrictions should I observe?
Continue to eat normally unless your doctor instructs you differently.
What are the potential negative effects of this medication?
Side effects of bamlanivimab and etesevimab injection are possible. Inform your doctor if any of the following symptoms are severe or persistent:
bleeding, bruising, pain, soreness, or swelling at injection site
Some of the Side effects might be severe. Call your doctor or get emergency medical attention if you suffer any of the following symptoms or those specified in the HOW section: fever, trouble breathing, changes in heart rate, weariness, weakness, or disorientation.
Other Side effects of bamlanivimab and etesevimab injection are possible. If you have any odd side effects while taking these drugs, contact your doctor.
If you have a significant adverse event, you or your doctor can report it to the FDA’s MedWatch Adverse Event Reporting programme online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
In the event of an emergency or an overdose
In the event of an overdose, dial 1-800-222-1222 for poison control. There is additional information accessible online at https://www.poisonhelp.org/help. If the person has collapsed, had a seizure, is having difficulty breathing, or cannot be woken, dial 911 immediately.
What else should I be aware of?
Keep all of your doctor’s visits.
Inquire with your chemist about bamlanivimab and etesevimab injection.
Continue to isolate as instructed by your doctor, and practise public health measures like as wearing a mask, social distance, and frequent hand washing.
It is critical that you keep a written record of all prescription and nonprescription (over-the-counter) medications you are taking, as well as any vitamins, minerals, or other dietary supplements. You should carry this list with you whenever you go to the doctor or are admitted to the hospital. It is also crucial to have this information on hand in case of an emergency.
Receiving injections of bamlanivimab and etesevimab should not be seen as a replacement for getting a COVID-19 vaccine. If you haven’t already been vaccinated against COVID-19, it’s important to discuss getting a vaccine with your healthcare provider to prevent the disease.
The information provided about bamlanivimab and etesevimab by the American Society of Health-System Pharmacists, Inc. was developed with a reasonable level of care and in accordance with professional standards in the field. Readers should be aware that bamlanivimab and etesevimab are not officially approved treatments for COVID-19 caused by SARS-CoV-2. Instead, they are being investigated and are currently available under an FDA emergency use authorization (EUA) for treating mild to moderate COVID-19 or preventing COVID-19 in specific outpatients, hospitalized children, and infants under 2 years old. The American Society of Health-System Pharmacists, Inc. does not make any explicit or implicit claims, including warranties of merchantability or fitness for a particular purpose, regarding the information and explicitly disclaims all such warranties.
Readers are cautioned that ASHP cannot guarantee the ongoing accuracy of the information, is not liable for any errors or omissions, and is not responsible for any consequences resulting from using this information. Readers should understand that decisions about drug therapy are complex medical choices that require the independent judgment of a qualified healthcare professional. The information provided here is intended for informational purposes only. The American Society of Health-System Pharmacists, Inc. does not endorse or suggest the use of any specific medication. The details provided about bamlanivimab and etesevimab should not be interpreted as personalized medical advice. Due to the evolving nature of drug information, it is advisable to consult with your doctor or pharmacist regarding the specific clinical use of any medications.
Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.