Zyvoxid Oral : Uses, Side Effects, Interactions


GENERIC NAME(S): Linezolid


Linezolid, sold under the trade name Zyvoxid among others. Zyvoxid is an antibiotic used to treat certain severe bacterial infections. It works by stopping the growth of bacteria.

This antibiotic only treats bacterial infections. It will not work for viral infection (such as common cold, flu). It is not necessary to use any antibiotic when it does not work for future transition.

Zyvoxid is also related to a class of drugs known as MAO inhibitors. It can increase the level of some natural substances (such as dopamine, norepinephrine, serotonin) in the body, which can increase the likelihood of some side effects and food and drug interactions. See How to Use, Side Effects, and Drug Interaction sections for more details.

How To Use Zyvoxid

Usually take Zyvoxid or Linezolid in the mouth or at least 12 hours directed by your doctor at the meal. Dosage is based on your medical condition and treatment response. For children, dosage is also based on age and weight, and they can be directed to take this medicine every 8 hours.

To stop the reaction of very serious hypertension, it is very important that you follow a special diet recommended by your doctor or dietician when you are taking this medicine, avoid foods and beverages that are old , Which include aged things, dried / aged meats and sausages (such as salami, liverwurst), preserved fish (such as spicy herring), such products that include Bud There are yeast (i.e cooked soup / gravy, homemade or sour bread), fermented foods (such as sauerkraut, kim chee), most of soybean products (such as soy sauce, tofu) Broad / fava beans, Red Wine, Sherry, Tap Beer, and Vermouth. Consult your doctor or dietician for more information and a complete list of other foods that contain tyramine which you should limit or avoid.

For the best effect, take this antibiotic evenly to the distance. To help you remember, take this medicine at the same time every day.

Continue to take this medication until the full amount of the quantity ends, even after the symptoms disappear after a few days. The infection can come back very quickly by closing the medication.

Tell your doctor if your condition is bad or bad.

Side Effects

Diarrhea, headache, nausea, vomiting or dizziness can occur. If any of these effects gets worse or worse, then tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed Zyvoxid or Linezolid because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if you have a serious side effect, including: deep / fast breathing, abnormal drowsiness, nausea / vomiting that does not stop, numbness of hands / feet, tiredness, abnormal fatigue, bleeding or hemorrhage.

If you have a very serious side effect, get medical help, including: muscle stiffness, increased sweating, change in vision (e.g blurred vision, changes in color vision, loss of vision), change in mental / mood (Such as movement, confusion), seizure.

Due to the type of resistant bacteria, this drug can rarely cause the intestinal severity (Clostridium difficile-associated diarrhea). This condition can occur during the treatment or during the months of the closure of the treatment months. Tell your doctor immediately if you develop: diarrhea that does not stop stomach pain, stomachache / spasms, blood / mucus.

If you have any of these symptoms, do not use diarrhea or opioid drugs because these products can make them worse.

Using this drug for prolonged or frequent periods can lead to oral thrush or yeast infection. If you see white spots, changes in vaginal discharge or other new symptoms in your mouth, contact your doctor.

This drug can increase serotonin and rarely cause a very serious condition, which is called serotonin syndrome / toxicity. The risk increases if you are taking other medicines which increase the serotonin, so tell your doctor or pharmacist about all the medicines that you take. Receive immediate medical help when some of the following symptoms develop: Fast heartbeats, hallucinations, loss of coordination, severe dizziness, unexplained fever, severe nausea / vomiting / diarrhea, muscle shaking, abnormal movement or restlessness

This drug can rarely cause the attack of hypertension (high blood pressure), which can be fatal. Many drug and food interactions can increase this risk (see how to use and drug interaction section). If any of these have serious side effects, seek medical help immediately: severe headache, fast / slow / irregular / fast heartbeat, chest pain, neck / cramps, severe nausea / vomiting, sweating / smelly skin (sometimes- Occasionally due to fever), broad pupils, vision changes (such as double / blurred vision), sudden sensitivity towards light (photophobia)

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Zyvoxid or Linezolid, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.

Before using this drug, tell your doctor or pharmacist your medical history, especially: high blood pressure, problems of blood / bone marrow (such as low red / white blood cells and platelets), some tumor conditions (e.g. pheochromocytoma, carcinoid syndrome), overactive thyroid, seizures.

Zyvoxid can make you dizzy. Alcohol or marijuana can make you feel more dizzy. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Limit alcoholic beverages. If you are using marijuana, talk to your doctor.

If you have diabetes, then the Zyvoxid can reduce your blood glucose. Regularly check your blood glucose as directed and share the result with your doctor. Tell your doctor immediately if you have symptoms of low blood sugar such as sudden sweating, shock, fast heartbeat, hunger, blurred vision, dizziness or twisting of hands / feet. Your doctor may need to adjust your diabetes medication, exercise program or diet.

Zyvoxid can not work because of live bacterial vaccines (like typhoid vaccine). Do not vaccinate / vaccinate while using this drug unless your doctor tells you.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

During pregnancy, this drug should be used only when it is clearly necessary. Discuss the risks and benefits with your doctor.

It is unknown if this medicine passes in breast milk. Consult your doctor before breastfeeding.


See also the usage section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription medicines and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some products that interact with this drug include:  diet pills/appetite suppressants (such as diethylpropion), drugs for attention deficit disorder (such as atomoxetine, methylphenidate) , apraclonidine,  bupropion,  buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, a certain combination product (dextromethorphan/quinidine), levodopa,  maprotiline, methyldopa, certain narcotic pain relievers (such as fentanyl, meperidine, methadone, tapentadol), certain drugs for Parkinson’s disease (such as entacapone, tolcapone), certain supplements (such as tryptophan, tyramine), tetrabenazine, tricyclic antidepressants (such as amitriptyline, doxepin), valbenazine.

If you are taking other medicines that increase serotonin then the risk of serotonin syndrome / toxicity increases. Examples include street drugs such as MDMA/”ecstasy,” St. John’s wort, certain antidepressants  (including  mirtazapine, SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), tramadol, certain “triptans” used to treat migraine headaches (such as rizatriptan,  sumatriptan, zolmitriptan), among others. The risk of serotonin syndrome / toxicity can be higher when you start or increase the dose of these medicines.

Some products can interact with Zyvoxid if you take them together, or even if you take them before or after taking the Zyvoxid. Tell your doctor or pharmacist whether you take anything in the list of products that can interact with this medicine, or increase the serotonin within 2 weeks before or after the Zyvoxid. Tell them also whether you have taken fluoxetine within 5 weeks before starting the Zyvoxid. Ask your doctor how much time to wait between starting or stopping any of these medicines and starting a Zyvoxid.

Taking other MAO inhibitors with this drug can be a serious (potentially fatal) drug interaction. Do not take any other MAO inhibitors (isocarboxazid, methylene blue, moclobemide,   phenelzine,   procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this drug. Most MAO inhibitors should not be taken for two weeks before and after treatment with this drug. Ask your doctor when to start or stop this medication.

Before using the Zyvoxid, report the use of drugs that can increase the risk of hypertensive crisis (high blood pressure), in which the herbal products (such as ephedra/ma huang), allergy And cold products (including  decongestants such as phenylephrine/pseudoephedrine), and stimulants (such as amphetamines, ephedrine, epinephrine). Zyvoxid should not be used with any of these drugs. Talk to your doctor or pharmacist for more information.

Although most antibiotics are unlikely to affect hormonal birth control, such as pills, patches, or rings, some antibiotics (Such as rifampin,  rifabutin) can reduce their effectiveness. This can lead to pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more information.

Over Dose

If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.


Do not share this medication with others.

This drug is prescribed for your current condition only. Do not use it later for any other infection until your doctor tells you.

Labs and / or medical tests (like whole blood count) should be done when you are taking this medication. If you take Zyvoxid for 3 months or more, or if you have vision changes, eye examination should also be done. Keep all medical and lab appointments.

Missed Dose

If you miss a dose, then as soon as you remember, take it. If it is near the next dose time, then leave the thesis dose. Take your next dose at regular times. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed not to do so, do not flush the medicines in the toilet and do not drain in the drain. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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