Zyban Oral : Uses, Side Effects, Interactions


GENERIC NAME(S): Bupropion Hcl


Bupropion, sold under the brand names Wellbutrin and Zyban among others. This medicine is used in combination with stop-smoking programs (e.g., support groups, counseling) to help you quit smoking. Zyban can reduce the symptoms of your nicotine withdrawal (e.g., irritability, anxiety, restlessness) and urge to smoke. Quitting smoking will reduce the risk of cancer along with your heart and lung disease.

This medicine is related to a class of drugs called antidepressants. It is not actually known how Zyban works to reduce the urge to smoke. It can work by restoring the balance of some natural chemicals (neurotransmitters) in the brain.

Discuss the risks and benefits of this drug, as well as other methods of quitting smoking (such as nicotine replacement therapy), with your doctor.

How to use Zyban

Before starting use of Zyban or Bupropion and when you receive a refill, read the Patient Information leaflet and medication guide available from your pharmacist. If you have any questions, consult your doctor or pharmacist.

Take this medicine from mouth, without food, usually three times a day. If the stomach is bad, then you can take this medicine with food. It is necessary to take at least 6 hours separately to reduce the risk of your doctor being guided or seizure.

Do not take more or less medication or take more than prescribed. Taking more than the recommended dose of Zyban may increase your risk of having a seizure. Do not take more than 150 mg as a dose, and do not take more than 450 mg per day.

Your dose is based on your medical condition and medical reaction. Your dose may gradually increase side effects such as sleepiness, and reduce risk of tourism. To avoid trouble in sleep, do not take this medicine even closer to sleep. Tell your doctor if there is a problem of sleeping.

Use this drug regularly so that it can get the most benefit. To help you remember, use it at the same time each day.

Do not stop taking this medicine without consultation with your doctor. When the drug suddenly stops, some conditions may get worse. Your dose may need to be gradually decreased.

You can take 4 or more weeks before paying attention to the full benefits of this medication. Continue to take this medicine directed by your doctor even after feeling better. Talk to your doctor if your condition does not improve or if it gets worse.

Side Effects

See also usage, precautions and warning sections.

Nausea, vomiting, dry mouth, headache, constipation, increased sweating, joints pain, sore throat, blurred vision, strange taste in the mouth, diarrhea, or dizziness can come. If any of these effects persists or worsens immediately, inform your doctor or pharmacist immediately.

Remember that your doctor has prescribed this drug because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Zyban can increase your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor immediately if any of these have potential but serious side effects: chest pain, unconsciousness, fast / fast / irregular heartbeat, hearing problems, ear ringing, severe headache, mental / mood swings (i.e. , Movement, anxiety, anxiety) confusion, hallucinations, memory loss), uncontrolled motion (shiver), abnormal weight loss or gain.

Tell your doctor immediately if any of these are rare but very serious side effects: muscle pain / tenderness / weakness.

If you have a very serious side effect, get medical help, including: pain in the eyes / swelling / redness, wide arms, changes in vision (such as watching rainbow around light at night).

Zyban can rarely cause a tour. If you have experience of a seizure, then seek immediate medical attention. If you have a seizure while taking a Zyban, then you should not take this medicine again.

There is no possibility of a very serious allergic reaction to this drug, but if this happens, seek immediate medical attention. Symptoms of a severe allergic reaction include: rash, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


See also the usage and warning section.

Before taking a Zyban or Bupropion, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.

Before using Zyban, tell your doctor or pharmacist your medical history, especially: visits or situations that affect your visits (brain / head injury, brain tumors, aneurysm, eating disorders such as Bulimia / Increase the risk of anorexia nervosa), dependence on alcohol / drugs ( benzodiazepines, narcotic pain medicines, cocaine and stimulants), diabetes, heart Diseases (e.g., heart failure, hypertension, recent heart attack), kidney problems, liver problems (e.g., cirrhosis), history of personal or family psychiatric disorder (e.g., bipolar / manic-depressive disorder), Personal or family history / effort of suicide ideas, personal or family history of glaucoma (angle-off type).

This drug should not be used if you are stopping regular use of sedative (including benzodiazepines such as lorazepam), medicines used to treat seizures or alcohol. Doing this can increase the risk of your tour.

Although abnormal, depression can lead to thoughts or suicide attempts. Tell your doctor immediately if you have any suicidal thoughts, there is a deteriorating depression, or some other mental / mood change (new or worrisome anxiety, movement, panic attacks, trouble sleep, irritability, hostile / angry feelings, impulsive actions , Severe restlessness) fast speech, unusual behavior change). Keep all medical appointments so that your doctor can closely monitor your progress and if necessary, adjust or change your medication.

Zyban can make you dizzy or affect your coordination. Alcohol or marijuana can make you feel more dizzy or affect your coordination. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Avoid alcoholic beverages. Alcohol can also increase the risk of your visit. If you are using marijuana, talk to your doctor.

Older adults may be more susceptible to the side effects of this drug, especially dizziness and memory loss. Dizziness can increase the risk of falling.

During pregnancy, this drug should be used only when it is clearly necessary. Since untreated mental / mood problems (such as depression, seasonal affection disorder, bipolar disorder) can be a serious condition, do not stop taking this medicine until your doctor prescribes it. If you are planning a pregnancy, become pregnant, or think that you may be pregnant, discuss the benefits and risks of using your medicine immediately during your pregnancy.

This medicine passes in breast milk and can have an undesirable effect on the nursing infant. Consult your doctor before breastfeeding.


See also the Precautions section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription medicines and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some products that interact with this drug include: codeine,  pimozide,  tamoxifen.

Taking the MAO inhibitor with this drug can be a cause of serious (potentially fatal) drug interactions. During treatment with this drug, avoid taking the MAO inhibitor (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most MAO inhibitors should not be taken for two weeks before and after treatment with this drug. Ask your doctor when to start or stop this medication.

Zyban may interfere with certain medical / laboratory tests (brain scan for Parkinson’s disease, including urine test for amphetamine), possibly giving incorrect results. Tell laboratory personnel and all your doctors that you use this medicine.

Over Dose

If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center. Symptoms of overdose may include: seizures, hallucinations, fast or slow heart rate, loss of consciousness.


Do not share this medication with others.

Tests like psychiatric / medical check-up or blood pressure monitoring can be done periodically to monitor your progress or to examine side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, then leave the missed dose and start your normal dose program again. Do not double the dose to catch up.


Store at room temperature away from light and moisture. There may be a strange odor in the Zyban tablets. It is normal and the use of medicine is still fine. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed not to do so, do not flush the medicines in the toilet and do not drain in the drain. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

4 thoughts on “Zyban Oral : Uses, Side Effects, Interactions

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