Tramadol Oral : Uses, Side Effects, Interactions



See also the warning section.

Tramadol is used to help reduce the risk of moderate to severe pain. Tramadol is similar to opioid (alcoholic) analgesic. It works to change the brain how your body feels and responds to the pain.

How To Use Tramadol HCL

Before starting the tramadol, read the medication guide provided by your pharmacist and every time you receive a refill. If you have any questions, ask your doctor or pharmacist.

Take Tramadol guided by your doctor, usually every 4 to 6 hours as needed to relieve pain. You can take this medicine with or without food. If you have nausea, it can be helpful to take this medicine with food. Ask your doctor or pharmacist about other ways to reduce nausea (such as shaking the head as much as possible by lengthening from 1 to 2 hours).

Dosage is based on your medical condition and treatment response. To reduce your risk of side effects, your doctor may direct you to start this medication on low dose and gradually increase your dose. Follow your doctor’s instructions carefully. The recommended maximum dose is 400 mg per day. If you are over 75 years of age, the recommended maximum dose is 300 mg per day. Do not increase your dose, take medication more often, or take longer than scheduled time. When instructed, stop the medication properly.

Pain medicines work best if they are used as the first symptom of pain. If you wait until the pain gets worse, the medication can not work.

If you are suffering from persistent pain (such as arthritis), then your doctor may instruct you to take long-term opioid medicines. In that case, this drug can be used for sudden (success) pain. Other painkillers (such as acetaminophen, ibuprofen) can also be determined. Ask your doctor or pharmacist about using tramadol safely with other medicines.

This medication may be the reason for the withdrawal response, especially if it has been used regularly for a long time or in higher doses. If you suddenly stop using this medicine then in such cases, symptoms of withdrawal (such as discomfort, water coming in the nose, nasal bleeding, sweating, muscle pain) can occur. To prevent withdrawal responses, your doctor may gradually reduce your dose. Consult your doctor or pharmacist for more information, and immediately report any refund responses.

When Tramadol is used for a long time, it can not work too. Talk to your doctor if this medicine stops working well.

Although it helps many people, but Tramadol can sometimes cause addiction. This risk can be high if you have any substance use disorder (like excess / drug or addiction of alcohol). Take this medicine properly to reduce the risk of addiction. Ask your doctor or pharmacist for more information.

Tell your doctor if your pain remains or worsens.

Side Effects

See also the warning section.

Nausea, vomiting, constipation, dizziness, dizziness, drowsiness, or headache can occur. After using Tramadol for a while, some of these side effects may be reduced. If any of these effects persists or worsens, tell your doctor or pharmacist immediately.

To prevent constipation, eat dietary fiber, drink plenty of water, and exercise. Consult your pharmacist to help select a laxative (such as a stimulant type with stool softener).

To reduce the risk of dizziness and lighthouse, slowly rise while sitting or lying down from the position of lying.

Remember that your doctor has prescribed this drug because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if you have any serious side effects, including: changes in mental / mood (such as movement, hallucinations), severe stomach / stomach ache, difficulty in urinating, signs of your adrenal glands work well (Like lack of appetite, abnormal fatigue, loss of weight)

If you have a very serious side effect, get immediate medical attention, including: fast / irregular heartbeat, severe dizziness, unconsciousness, seizures.

Tramadol can increase serotonin and rarely cause a very serious condition, which is called serotonin syndrome / toxicity. The risk increases if you are taking other medicines that increase the serotonin, so tell your doctor or pharmacist about all the medicines that you take (see the drug interaction section). Get medical help immediately when some of the following symptoms develop: Fast heartbeats, hallucinations, loss of coordination, severe dizziness, severe nausea / vomiting / diarrhea, muscle shaking, unexplained fever, abnormal movement or restlessness

Tramadol is converted into a strong opioid drug in your body. In some people, this change happens more quickly and completely than usual, which increases the risk of very serious side effects. If you notice any of the following, get medical help immediately: slow breathing / shallow breathing, severe sleepiness / wake up, illusion

A very serious allergic reaction to this drug is rare. However, if you see any of the following symptoms, seek medical help immediately: Rashes, itching / swelling (especially the face / tongue / throat), severe dizziness, shortness of breath

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking tramadol, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.

Before using Tramadol, tell your doctor or pharmacist your medical history, especially: brain disorders (such as head injury, tumors, seizures), problems in breathing (such as asthma, sleep apnea, chronic obstructive pulmonary Disease-COPD), kidney disease, liver disease, mental / mood disorders (such as delusions, depression, thoughts of suicide), personal or family history of a substance Diseases in health (such as drugs / alcohol addiction or overuse), stomach / intestinal problems (e.g. obstruction) constipation, diarrhea due to infection, paralysis ileus), difficulty in urinating (as the cause of increased prostate), gall bladder Disease of the pouch, pancreatitis, obesity

Tramadol may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or deaf. Unless you can safely do this, do not drive, use machinery, or do anything that requires caution. Avoid alcoholic beverages. If you are using marijuana, talk to your doctor.

Tramadol can cause a condition that affects the heart rhythm (QT prolonged). Prolonged Qt can rarely cause serious (rarely fatal) fast / irregular heartbeat and other symptoms (such as severe dizziness, unconsciousness) that require immediate medical attention.

If you have some medical conditions or QT prolonged other medications are taking Qt can increase the risk of prolonging. Before using Tramadol, tell your doctor or the pharmacist of all medicines you take, and if you have any of the following conditions: Some heart problems (heart failure, slow heart beat, QT in EKG) Prolonged), family history of some heart problems (longevity in Qt EKG, sudden cardiac death).

Lower levels of potassium or magnesium in the blood can also increase the risk of QT being long. This risk can increase if you use certain medications (such as diuretic / “water tablets”) or if you have conditions like severe sweating, diarrhea or vomiting. Talk to your doctor about using tramadol safely.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

Some babies may be more sensitive to severe side effects of tramadol, such as excessive sleep, confusion, or slow / shallow breathing. (See also the warning section.)

Older adults may be more sensitive to the side effects of this drug, especially confusion, dizziness, drowsiness, slow / shallow breathing, and QT prolongation (see above).

During pregnancy, Tramadol should be used only when explicitly necessary. It can harm an unborn child. Discuss the risks and benefits with your doctor. (See also the warning section.)

This medicine passes in breast milk and can have undesirable effects on the nursing infant, such as abnormal sleep, difficulty in feeding or difficulty in breathing. Breastfeeding is not recommended when using this medicine. Consult your doctor before breastfeeding.


See also the warning section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some products that interact with this drug include: Some pain medications (mixed opioid agonist-antagonist such as pentazocine, nalbuphine, butorphanol), naltrexone.

Taking the MAO inhibitor with this drug can be a cause of serious (potentially fatal) drug interactions. During treatment with this drug, avoid taking the MAO inhibitor ((isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most of the MAO inhibitors should not be taken for two weeks before treatment with this drug. Ask your doctor about when to start or stop this medication.

If you are taking other medicines that increase serotonin then the risk of serotonin syndrome / toxicity increases. Examples include MDMA / “Bliss,” St. John’s Plant, some antidepressants (such as fluoxetine/paroxetine such as SSRI, SLRI such as duloxetine/venlafaxine)). The risk of serotonin syndrome / toxicity can be high when you start or increase the dose of these medicines.

Other medicines can affect the removal of tramadol from your body, which can affect how tramadol works. Examples include the use of  quinidine, azole antifungals (such as itraconazole), HIV drugs (such as ritonavir), macrolide antibiotics (e.g erythromycin), rifamycins (such as rifampin), drugs used to treat seizures (such as carbamazepine).

If Tramadol is taken with other products that can cause sleepiness or breathing problem, then the risk of serious side effects (such as slow / shallow inhalation, severe sleepiness / dizziness) can increase. Tell your doctor or pharmacist whether you have other products such as other opioid pain or relief from cough (such as codeine, hydrocodone), alcohol, marijuana, sleep or anxiety medications (e.g,  alprazolam,  lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the label on all your drugs (like allergy or cough-and-cold products), because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This drug can interfere with some laboratory tests (including amylase / lipase levels), possibly due to false test results. Ensure that the lab staff and all your doctors know that you use this medicine.

Over Dose

If someone is treated and has serious symptoms such as difficulty in getting out or breathing, if available, then give them Naloxone, if call 911. If the person is awake and there is no symptoms, then call immediately a venom control center. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center. Symptoms of overdose may include: slow breathing, slow / irregular heartbeats, coma, seizures.


Do not share this medication with others. Sharing it is against the law.

Tramadol is prescribed for your current condition only. Do not use it for any other condition unless your doctor is asked to do so. In that case a different medication may be necessary.

Ask your doctor or pharmacist if you have Naloxone available for the treatment of opioid overdose. Teach your family or family members about the signs of an opioid overdose and how it is treated.


Store at room temperature away from light and moisture. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

Leave a Reply

Your email address will not be published. Required fields are marked *