Spironolactone Oral : Uses, Side Effects, Interactions


COMMON BRAND(S): Aldactone

GENERIC NAME(S): Spironolactone


Spironolactone is used to treat high blood pressure and heart failure. Reducing hypertension helps in preventing stroke, heart attack and kidney problems. This is done due to swelling (edema) due to some conditions (such as heart failure, liver disease), to remove excess fluid and improve symptoms such as respiratory problems.

Spironolactone is also used to treat low levels of potassium and conditions in which the body is using too much of a natural chemical (aldosterone).

Spironolactone is known as a “water pill” (potassium-sparing diuretic).

How To Use Spironolactone

Take this medicine from the mouth, as directed by your doctor. Take it with food or milk when the stomach gets worse. It is best to take your dose in the day (before 6 o’clock in the morning) to prevent night from urinating to urinate in the night. If you have any questions, consult your doctor or pharmacist.

If you are using the liquid form of Spironolactone then shake the bottle well before each dose. Measure the dose carefully using special measuring instruments / spoon. Do not use domestic spoon because you can not get the right dose. You can take the liquid form of this medicine with or without food, but it is important to choose a method and take it with every dose in the same way.

Dosage is based on your medical condition and medical reaction. In children, dosage is also based on body weight.

Take Spironolactone regularly so that it can get the most benefit. Remember to use it on the same time (s) as directed. It is important to continue taking this medicine even if you feel OK. Most people with high blood pressure do not feel sick.

Take this medicine exactly as it is prescribed. Do not increase your dose, take it more than it has been fixed, or stop using this medicine without consulting your doctor first. When the drug suddenly stops, your condition may worsen.

Inform your doctor if your condition gets worse (e.g, if you notice an increase in your regular blood pressure reading).

Side Effects

Sleepiness, dizziness, dizziness, stomach upset, diarrhea, nausea, vomiting or headache can occur. To reduce the lighthouse, slowly rise up while sitting or lying down from the position of lying. If any of these effects persists or worsens immediately, inform your doctor or pharmacist immediately.

Remember that your doctor has prescribed Spironolactone because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if you have a serious side effect, including: increased thirst, signs of kidney problems (such as changes in urine volume), changes in mental / mood, abnormal fatigue / weakness, muscle spasms, Changes in menstrual periods, men’s breast pain, gynecomastia, sexual function problems, symptoms of infection (e.g, fever, constant throat) ), Severe stomach / abdominal pain, persistent nausea / vomiting, vomit that looks like ground coffee, urine, yellowing eyes / skin, easy bruising / bleeding.

Spironolactone can have high levels of potassium, especially in patients having renal problems. If the treatment is not done, then the level of excess potassium can be fatal. Tell your doctor immediately if you see any of the following serious side effects: slow / irregular heart beat, muscle weakness.

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Spironolactone, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.

Before using Spironolactone, tell your doctor or pharmacist your medical history, especially: kidney problems, liver problems, untreated mineral imbalance (such as high potassium, low sodium), adrenal gland function (Addison’s disease) Decreased.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

Spironolactone can increase your potassium level. Consult your doctor or pharmacist before potassium supplements or potassium before using the option of salt. Limit high food items in potassium such as bananas, tomatoes, potatoes and low salt milk. Consult your doctor or pharmacist for more information, including recommendations.

This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or deaf. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Limit alcoholic beverages. If you are using marijuana, talk to your doctor.

Older adults may be more susceptible to the side effects of this drug, especially the effect on potassium (see side effects section).

Spironolactone should be used only when explicitly required during pregnancy. Discuss the risks and benefits with your doctor.

This medicine passes through breast milk but there is no possibility of harm to a nursing infant. Consult your doctor before breastfeeding.


See also the Precautions section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription medicines and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some of the products that interact with this drug include: Lithium, drugs that increase the level of potassium in the blood (such as amiloride,  cyclosporine,  eplerenone, tacrolimus, triamterene, birth control pills containing drospirenone).

Some products contain elements that can increase your blood pressure or cause bad swelling. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough and cold products, diet aids, or NSAIDs such as ibuprofen / naproxen).

Spironolactone can interfere with some laboratory tests (including levels of digoxin or cortisol), which may lead to incorrect test results. Ensure that the lab staff and all your doctors know that you use this medicine.

Over Dose

If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.


Do not share this medication with others.

Labs and / or medical tests (such as kidney / liver function, blood mineral level such as potassium) should be periodically monitored for monitoring your progress or checking side effects. Consult your doctor for more details.

If you are taking this medicine for high blood pressure, changes in lifestyle like stress reduction programs, exercise and dietary changes can increase the effectiveness of this drug. Talk to your doctor or pharmacist about lifestyle changes that can benefit you.

Check your blood pressure regularly while taking this medication. Discuss with your doctor and learn how to monitor your own blood pressure. Please inform the doctor of your blood pressure reading.

Missed Dose

If you miss a dose, then as soon as you remember, take it. If it is near the next dose time, then leave the thesis supplement and start your normal dose program again. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed not to do so, do not flush the medicines in the toilet and do not drain in the drain. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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