Simvastatin Oral : Uses, Side Effects, Interactions
Simvastatin is used to help reduce “bad” cholesterol and fat (such as LDL, triglycerides) with a proper diet and enhances “good” cholesterol (HDL) in the blood. It is related to a group of drugs called “statins”. It works by reducing the amount of cholesterol produced by the liver. Reducing cholesterol and triglycerides and reducing “good” cholesterol reduces the risk of cardiovascular disease and helps prevent stroke and heart attack.
In addition to eating a proper diet (such as low cholesterol / low fat diet), changes in other lifestyle that can help this drug work better include exercise in it, lose weight and more smoking. Consult your doctor for more details.
How to use simvastatin
Take this medicine from mouth, as directed by your doctor, usually once in the evening. If you are using the tablet form of this medicine, you can take this medicine with or without food.
If you are using the liquid form of this medicine, then take this medicine an empty stomach. Shake the bottle well for at least 20 seconds before each dose. Measure the dose carefully using special measuring instruments / spoon Do not use domestic spoon because you can not get the right dose.
Dosage is based on your medical condition, treatment response, age and other medicines you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including Prescription Drugs, Nonprescription Drugs and Herbal Products). Chinese patients taking niacin may need less dose of simvastatin. Ask your doctor for more information.
Normal maximum dose of this drug is 40 mg in one day. If you have been instructed to take more than 40 milligrams from your doctor, continue on the same dose. However, talk about the risks and benefits of your high dose immediately or with it.
Do not increase your dose or take this medicine more than it has been fixed. There will be no improvement in your situation, and the risk of serious side effects can increase.
Avoid eating grapes or grapes while using this drug, unless your doctor tells you otherwise. Grapes can increase the amount of this drug in your bloodstream. Contact your doctor or pharmacist for more information.
Take this medication regularly so that it can get the most benefit. Remember to take it at the same time every day. It is important to continue taking this medicine even if you feel OK. Most people with high cholesterol or triglycerides do not feel sick.
It is very important to continue to follow the advice of your doctor about diet and exercise. You can take up to 4 weeks to get the full benefit of this drug.
Remember that your doctor has prescribed this drug because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.
A small number of people who take Simvastatin may have light memory problems or confusion. If these are rare effects, talk to your doctor.
Rarely, statins can cause diabetes or deteriorate. Talk to your doctor about the benefits and risks.
Simvastatin can rarely cause muscle problems (which can rarely lead to very severe conditions called rhabdomyolysis and autoimmune myopathy). Tell your doctor immediately if you develop any of these symptoms during treatment and if these symptoms persist after your doctor stops this medication: muscular pain / tenderness / weakness (especially fever or abnormal With fatigue), symptoms of kidney problems (such as change in urine amount).
This drug can rarely cause liver problems. If you notice any of the following rare but serious side effects, then tell your doctor immediately: Yellow eyes / skin, deep urine, severe stomach / stomach pain, persistent nausea / vomiting.
A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, difficulty breathing.
This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.
Before taking Simvastatin, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.
Before using Simvastatin, tell your doctor or pharmacist your medical history, in particular: liver disease, kidney disease, alcohol use.
Before surgery, tell your doctor or dentist about all the products you use (including prescription medications, nonprescription drugs and herbal products).
Limit alcoholic beverages Daily use of alcohol can increase your risk for liver problems, especially when combined with simvastatin. Ask your doctor or pharmacist for more information.
Older adults may be more susceptible to the side effects of this drug, especially for muscle problems.
This drug should not be used during pregnancy. Simvastatin can harm an unborn child. Therefore, it is important to prevent pregnancy when taking this medicine. For more information, consult your doctor and discuss the use of reliable forms of reliable control (such as condoms, birth control pills) while taking this medication. If you become pregnant or you feel that you may be pregnant, then tell your doctor immediately.
It is unknown if this medicine passes in breast milk. Due to the potential risk to the baby, it is advisable not to breastfeed while using this drug. Consult your doctor before breastfeeding.
See also the usage section.
Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.
Some products that interact with this drug include: “blood thinner” (such as warfarin), cyclosporine, danazol, gemfibrozil.
Other medicines can affect the removal of Simvastatin from your body, which can affect the way Simvastatin works. Examples include some azole antifungal (such as itraconazole, ketoconazole, posaconazole, voriconazole), boceprevir, cobicistat, colchicine, delavirdine, macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, HIV protease inhibitors (such as nelfinavir, ritonavir), telaprevir, telithromycin, among others.
When you are taking Simvastatin, do not take any red yeast rice product as some red yeast rice products may also contain a statins called lovastatin. Taking simvastatin and red yeast rice products together can increase your risk of severe muscular and liver problems.
If someone is treated and has serious symptoms such as difficulty in getting out or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.
Do not share this medication with others.
Labs and / or medical tests (such as blood cholesterol / triglyceride levels) should be periodically monitoring your progress or checking side effects. Consult your doctor for more details.
If you miss a dose, then as soon as you remember it, take it. If it is near the next dose time, then leave the thesis dose and set your normal dose. Do not double the dose to catch up.
Keep away from light and moisture at room temperature. The temperature of the storage varies according to the different manufacturers, so consult your pharmacist for more information. Do not fridge or freeze. Do not store in the bathroom. Leave the medicine suspension form one month after opening the bottle, even if the medicine remains. Keep all medications away from children and pets.
Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.
Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.