Rhabdomyolysis: Symptoms, Causes, and Treatments


Rhabdomyolysis is a serious syndrome due to muscle injury directly or indirectly. This results in the death of muscle fibers and their content leaving the bloodstream. This can lead to serious complications like kidney failure. This means that the kidneys can not get rid of useless and concentrated urine. In rare cases, rhabdomyolysis can also cause death. However, early treatment often brings a good result. Here you need to know about rhabdomyolysis.

Reasons for Rhabdomyolysis

There are many painful and nontraumatic causes of Rhabdomyolysis. In the first category, the reasons include:

•  A crush injury such as an auto accident, falling, or building collapse
•  Long-lasting muscle compression, such as falling due to prolonged stabilization or fainting on a harsh surface during illness or under the influence of alcohol or drug.
•  Electric shock injuries, lightning strikes, or third-degree burns
•  Poison of snake or insect bites

Contraceptive causes of Rhabdomyolysis include:

•  Use of alcohol or illegal drugs such as heroin, cocaine or amphetamine
•  Extreme muscle tension, especially in someone who is untrained athlete; It can also happen in the elite athletes, and it can be more dangerous if there is more muscle mass to break.
•  Use of drugs such as antipsychotics or statins, especially given in high doses
•  Too much body temperature (hyperthermia) or heat stroke
•  Trembling or trembling shakes
•  Metabolic disorders such as diabetic ketoacidosis
•  Due to the lack of enzyme of congenital muscle such as muscular disease or Duchenne’s muscular dystrophy
•  Viral infections such as flu, HIV or herpes simplex virus
•  Bacterial infection leading to toxins in tissues or bloodstream (sepsis)
•  In the previous history of Rhabdomyolysis, the risk of rhabdomyolysis increases again.


Rhabdomyolysis Signs and Symptoms

Signs and symptoms of rhabdomyolysis can be difficult to pinpoint. This is quite true because the course of rhabdomyolysis is different, depending on its cause. And, the symptoms can occur in one area of ​​the body or can affect the whole body. Also, complexities may occur in early and later stages.

Rhabdomyolysis is “classic triad” of symptoms: muscle pain in the lower part of the shoulders, thighs or back; Muscle weakness or difficulty in moving hands and feet; And reducing dark red or brown urine or urine. Keep in mind that half of the people with the condition may not have any symptoms related to the muscles.

Other common symptoms of Rhabdomyolysis include:

•  Stomach ache
•  Vomiting
•  Fever, fast heart rate
•  Illness, dehydration, fever, or lack of consciousness

A blood test for creatine kinase, a product of muscle breakdown and urine test for hemoglobin, a relative of hemoglobin from the damaged muscles can help to diagnose Rhabdomyolysis (although in half of the cases, the hemoglobin test can come negative is ). Other tests can detect other problems, can confirm the cause of rhabdomyolysis or examine the complications.

The general complications of rhabdomyolysis include high levels of potassium in the blood, which can lead to irregular heartbeat or cardiac arrest and renal damage (which is up to half of patients). One of the four also develop problems with their liver. A condition called compartment syndrome can also occur after fluid resuscitation. This severe compression of veins, blood vessels and muscles can cause problems with tissue damage and blood flow.

Rhabdomyolysis Treatment

Early diagnosis and treatment are key to rhabdomyolysis and its cause are a successful result. You can expect complete recovery with prompt treatment. Doctors can also reverse kidney damage. However, if compartment syndrome is not treated early, it can cause permanent damage.

If you have rhabdomyolysis, then you will be admitted to the hospital to get treatment for the cause. Intravenous (IV) treatment with fluid helps in maintaining urine production and prevent kidney failure. Rarely, dialysis treatment may be needed so that your kidneys can help to cure waste products. The management of electrolyte abnormalities (potassium, calcium and phosphorus) helps protect your heart and other organs. If there is a risk of muscle damage or nerve damage from compartment syndrome, you may need a surgical procedure (fasciotomy) to relieve the stress or damage to the pressure and circulation. In some cases, you may need to be in the Intensive Care Unit (ICU) to allow close monitoring.

Most causes of Rhabdomyolysis are reversible.

If rhabdomyolysis is related to a medical condition, such as diabetes or thyroid disorder, then appropriate treatment for medical conditions will be required. And if rhabdomyolysis is related to a drug or medicine, then its use will be prevented or replaced with an alternative.

After treatment, discuss with your doctor any necessary range of diet or activity. And, of course, avoid any possible causes of rhabdomyolysis in the future.

One thought on “Rhabdomyolysis: Symptoms, Causes, and Treatments

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