Prasugrel : Uses, Side Effects, Interactions



Prasugrel is used by patients with heart disease (recently heart attack, unstable angina) with aspirin, which passes through a certain cardiac process (angioplasty). This medicine helps prevent other serious cardiovascular / blood vessel problems (such as heart attack, stroke, blood clots in stents). It prevents platelets from sticking together and prevents harmful blood clots from forming. This “anti-platelet” effect helps the blood flow smoothly to your body.

How to use Prasugrel Tablet

Read the medication guide and, if available, the patient information sheet is provided by your pharmacist before you start taking Prasugrel and every time you get a refill. If you have any questions, ask your doctor or pharmacist.

Guided by your doctor of mouth or without food, usually take this medicine once a day. Your doctor may direct you to take this medication with low-dose aspirin (usually on a diet of 81-325 milligrams a day). Follow your doctor’s instructions carefully.

Taking Prasugrel as guided is very important. Do not increase your dose or take this medicine more than it has been fixed. There will be no improvement in your situation, and the risk of your side effects will increase. Also, do not stop using this drug unless directed by your doctor.

Dosage is based on your medical condition, weight and treatment response.

Use this medication regularly to get the most benefit. To help you remember, take it every day at the same time.

Side Effects

Headache, nausea, hemorrhage and stomach can worsen. If any of these effects persists or worsens, tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed this drug because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Prasugrel can cause severe bleeding. Tell your doctor immediately if you have any signs of severe bleeding, including: abnormal pain / swelling / discomfort, abnormal injury, cuts or long periods of bleeding from the gums, steady / persistent nose bleeding, abnormally heavy / Chronic menstrual flow, blood coughing / black / terry stool, bloody urine, vomiting is bloody or looks like a coffee ground, severe headache, dizziness / unconsciousness, breath Problems of chest pain, difficulty in swallowing

Prasugrel rarely has caused a certain blood disorder (thrombotic thrombocytopenic purpura). If you develop symptoms of this blood disorder, seek medical help, including: changes in vision, slim speech, confusion, yellowing of the skin, blackening of the skin, signs of kidney problems (such as urination Change in volume), abnormal weakness / fatigue, unexplained fever.

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, immediately seek medical help, including: severe rashes, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Prasugrel, tell your doctor or pharmacist whether you are allergic to it; Or similar antiplatelet drugs (thienopyridines such as clopidogrel); Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.

Before using Prasugrel, tell your doctor or pharmacist your medical history, especially: blood disorder (like hemophilia), bleeding problem (such as bleeding / intestinal bleeding, bleeding in the brain), blood in the brain Clots (stroke), transient ischemic attack (TIA), recent major injury / surgery, liver disease, stomach / intestinal ulcers.

Before doing surgery or any medical / dental procedure (including Heart Bypass Surgery – CABG), tell your doctor or dentist about all the products you use (including Prescription Drugs, NonPrescription Drugs and Herbal Products) ).

To reduce the possibility of cuts, injuries or injuries, take precautions from sharp items such as razors and nail cutters and avoid activities like contact sports.

Prasugrel can cause bleeding in the stomach. Daily use of alcohol while using this drug will increase your risk for stomach bleeding. Limit alcoholic beverages Ask your doctor or pharmacist how much alcohol you can drink.

Older adults (75 years or more) may be more susceptible to the side effects of this drug, especially bleeding. Discuss the risks and benefits with your doctor.

During pregnancy, Prasugrel should be used only when explicitly necessary. Discuss the risks and benefits with your doctor.

It is unknown if this medicine passes in breast milk. Consult your doctor before breastfeeding.


Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

A product that can communicate with this drug: Tipranavir.

Prasugrel is sometimes used with other medicines, which have “blood diluted” or anti-platelet effects, such as aspirin or heparin. When these combination is determined by your doctor, you will need to closely monitor to reduce the risk of bleeding. Keep all medical and laboratory appointments.

Carefully check the label of all the prescriptions and non-prescription medicines containing painkillers / aspirin (aspirin, NSAIDS, such as ibuprofen, naproxen) of many medicines, which can increase the risk of bleeding after taking this medication. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually on a diet of 81-325 mg in a day), then you should continue it until Until your doctor does not give you directions. Ask your doctor or pharmacist for more information.

Over Dose

If someone is treated and has serious symptoms such as difficulty in getting out or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.


Do not share this medication with others.

Labs and / or medical tests (such as full blood count) should be periodically monitoring your progress or checking side effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, then as soon as you remember it, take it. If it is near the next dose time, then leave the thesis dose and set your normal dose. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Store the medicine in the original bottle to protect from moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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