Plavix Oral : Uses, Side Effects, Interactions


GENERIC NAME(S): Clopidogrel




Clopidogrel, sold as the brandname Plavix among others. Plavix is used to prevent heart attack (recent heart attack), recent stroke, or heart attack and stroke with circulatory disease (peripheral vascular disease).

It is also used to treat new / worsening chest pain (new heart attack, unstable angina) with aspirin and to keep blood vessels open and to prevent blood clots after some procedures (such as cardiac stent) .

Plavix works by sticking platelets together and prevents them from forming harmful clots. This is an antiplatelet drug. It helps in flowing the blood smoothly in your body.

How to use Plavix

Before starting Plavix or Clopidogrel, read the medication guide given by your pharmacist and every time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take Plavix with or without mouth directed by your doctor, usually daily once daily. Take this medication regularly to get the most benefit of this. To help you remember, take it every day at the same time.

The dose and length of treatment is based on your medical condition and treatment response. If you are taking this medication to prevent clotting after stent implant or other procedure, then this medicine is prescribed by your doctor according to the procedure for several months with aspirin for years (depending on the type of stent / procedure). Do it. Consult your doctor for more information and about the risks of early stopping. It is important to continue taking this medicine even if you feel OK. Do not stop taking this medicine without consulting your doctor.

Avoid eating grapes or grapes while using Plavix, unless your doctor or pharmacist says you can do it safely. The possibility of grapes side effects may increase with this drug. Ask your doctor or pharmacist for more information.

If you have any indication that this drug is not working, get medical help immediately, such as a new heart attack or symptoms of stroke (such as chest / jaw / left hand pain, shortness of breath, abnormal sweat, One side weakness) body, slim speech, sudden sight change, delusion).

Side Effects

Easy bleeding / wounds, stomachache / pain, diarrhea, and constipation can occur. If any of these effects persists or worsens, tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed Clopidogrel or Plavix because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Although unlikely, there may be severe bleeding in the stomach, intestine, eyes or brain. In addition, Plavix can rarely cause a very serious blood disorder (thrombotic thrombocytopenic purpura-TTP). Symptoms may appear at any time after starting this drug. Get medical help immediately after any of these symptoms: severe stomach / stomach ache, uncontrolled bleeding with gums or nasal, bloody / black colored feces, confusion, fever, excessive skin pallor, purple skin spots, Unconsciousness, high heart beat, sudden severe headache, abnormal weakness / fatigue, vomiting with blood or that looks like coffee grounds, slim speech, change in sight, seizures, yellow eyes Take / skin, bloody / red / pink / deep urine, signs of renal problems (such as urine changes) urine).

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, shortness of breath

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking clopidogrel or Plavix, tell your doctor or pharmacist whether you are allergic to it; Or similar antiplatelet drugs (thienopyridines such as prasugrel); Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.

Before using Plavix, tell your doctor or pharmacist your medical history, especially: the condition of bleeding (such as stomach ulcers, brain / eye bleeding), recent surgery, severe injury / trauma, liver disease , Bleeding diseases (like hemophilia).

To reduce the possibility of cuts, injuries or injuries, take precautions from sharp items such as razors and nail cutters and avoid activities like contact sports.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products). Your doctor may instruct you to stop Plavix for at least 5 days before surgery. Do not stop taking Plavix without first talking to your heart doctor (cardiologist).

Plavix can cause bleeding in the stomach. Daily use of alcohol while using this drug can increase your risk for stomach bleeding. Limit alcoholic beverages Ask your doctor or pharmacist how much alcohol you can drink.

During pregnancy, Plavix should be used only when explicitly necessary. Discuss the risks and benefits with your doctor.

It is unknown if this medicine passes in breast milk. Consult your doctor before breastfeeding.


See also the usage section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

A product that can communicate with this drug: Tipranavir.

If you are currently taking aspirin, consult your doctor immediately and ask if continuing or closing it with this drug is your specific condition (use of aspirin and clopidogrel or Plavix after the coronary stent procedure, or some heart conditions Can be done later). If you are not currently taking aspirin, consult your doctor before starting it for any medical condition.

Other medicines can affect the removal of Plavix from your body, which can affect the way Plavix works. Examples include some acid reducer (proton pump inhibitors / PPIs such as omeprazole,  esomeprazole),  fluvoxamine,  fluoxetine,  cimetidine,  fluconazole,  ketoconazole,  voriconazole,  etravirine,  felbamate,  and ticlopidine. Ask your doctor or pharmacist immediately for more information.

Plavix can slow down the removal of other drugs from your body, which can affect how they work. Examples of affected medicines include dasabuvir, repaglinide, and others.

Carefully review all the prescription and non-prescription medication labels from the painkillers of many medicines / fever recipients (NSAIDs such as ibuprofen, naproxen, or aspirin). These medicines can increase the risk of bleeding / antiplatelet effect when used with Plavix. Ask your pharmacist about using these products safely.

Over Dose

If someone is treated and has serious symptoms such as difficulty in getting out or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.


Do not share this medication with others.

Laboratory and / or medical tests (such as full blood count) can be used to periodically monitor your progress or examine side-effects. Consult your doctor for more details.

Missed Dose

If you miss a dose, then as soon as you remember it, take it. If it is near the next dose time, then leave the thesis dose. Take your next dose at regular times. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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