Pariet – Uses, Side Effects, Interactions



Pariet (Rabeprazole) is used to treat certain stomach and esophagus problems (such as acid reflux, ulcer). It works by reducing the amount of acid produced in your stomach. It relieves heartburn, difficulty in swallowing and persistent cough symptoms. This medicine helps in stomach and esophagus to cure acid damage, helps in preventing ulcers, and can help to prevent esophageal cancer. Pariet is related to a class of drugs known as proton pump inhibitors (PPIs).

How to use Pariet

Before you take the Pariet, read the medication guide and patient information sheet from your pharmacist and every time you get a refill. If you have any questions, ask your doctor or pharmacist.

If you are using pills, take your dose with or without food as directed by your doctor, usually 1 to 2 times daily. Swallow the tablet with whole water. Do not crush, chew or divide the tablet. Doing this increases the risk of side effects, you can release all medicines at a time.

If you are using capsules, take dose 30 minutes before your doctor prescribes diet, usually once daily. Do not swallow capsules completely. Open the capsule and sprinkle the small amount of soft food (such as apple or curd) or liquid on the liquid. The food or liquid you use should be at room temperature or below. Swallow the whole mixture within 15 minutes of preparing it. Do not chew or crush the prepared mixture.

The dose and length of treatment is based on your medical condition and treatment response. In children, dosage is also based on weight.

If necessary, antacids can be taken with Pariet. If you are also taking sucralfate, then take a Pariet at least 30 minutes before sucralfate.

Use Pariet regularly to get the most benefit. To help you remember, take it every day at the same time. Continue taking this medicine for a fixed length of treatment, even if you are feeling better.

Tell your doctor if your condition persists or worsens. Over time, the risk of side effects increases. Ask your doctor how long you should take this medicine.

Side Effects

Headache can occur. If this effect remains or worsens, tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed this drug because he or she has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Tell your doctor immediately if you have any serious side effects, including the following: Lower magnesium blood level symptoms (such as abnormally fast / slow / irregular heartbeats, frequent muscle spasms, visits), Lupus signs (e.g Pimples and cheeks on the nose, pain of new or worsening joints).

Due to the type of bacteria, Pariet can rarely cause the intestinal severity (Clostridium difficile-associated diarrhea). If you have any of the following symptoms, do not use anti-diarrhea or opioid drugs because these products can make them worse. Tell your doctor immediately if you develop: Constant diarrhea, stomach or stomach aches / cramps, fever, blood / sputum in your stools

Rarely, proton pump inhibitors (such as Pariet) cause a lack of vitamin B12. The risk is increased if they are taken for long periods of time (for 3 years or more). Tell your doctor immediately if you develop symptoms of vitamin B12 deficiency (such as abnormal weakness, tongue in the throat, or numbness / tingling of hands / feet)

A very serious allergic reaction to Pariet is rare. However, if you see symptoms of a serious allergic reaction, get immediate medical help, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, shortness of breath, Symptoms of renal problems (such as changes in urine)

This is not a complete list of possible side effects. If you see other effects, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Pariet, tell your doctor or pharmacist whether you are allergic to it; Or for similar medicines (such as lansoprazoleomeprazole); Or if you have any other allergens. This product may contain passive elements, which may cause allergic or other problems. Talk to your pharmacist for more details.

Before using Pariet, tell your doctor or pharmacist your medical history, in particular: liver disease, Lupus.

Some symptoms may actually be signs of a more serious condition. If you get immediate medical help: jealousy / sweating / dizziness with heartburn, chest / jaw / hand / shoulder pain (especially shortness of breath, abnormal sweating), unexplained weight loss

Proton pump inhibitors (such as Pariet) can increase your risk for bone fractures, especially in long-term use, high dose and in older adults. Talk to your doctor or pharmacist about ways to prevent bone loss / fracture, such as calcium (such as calcium citrate) and vitamin D supplements.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

During pregnancy, Pariet should be used only when explicitly necessary. Discuss the risks and benefits with your doctor.

It is unknown if this medicine passes in breast milk. However, similar drugs undergo breast milk. The effect on a nursing infant is unknown. Consult your doctor before breastfeeding.


Also see how to use the section.

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

A product that can interact with Pariet: methotrexate (especially high-dose treatment)

Some products require acids in the stomach so that the body can absorb them properly. Pariet reduces stomach acids, so it can change how well these products work. Some affected products include ampicillin, atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, certain azole antifungals (itraconazole, ketoconazole, posaconazole).

Pariet can interfere with some laboratory tests, possibly causing false test results. Ensure that the lab staff and all your doctors know that you use this medicine.

Over Dose

If someone is treated and has serious symptoms such as difficulty in getting out or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.


Do not share this medication with others.

If your doctor gives you instructions on how to use this medication for a long period of time, then laboratory and medical tests (such as a magnesium blood test, vitamin B-12 levels) monitor your progress or check the side effects Can be done from time to time. Keep all regular medical and laboratory appointments.

Missed Dose

If you miss a dose, then as soon as you remember it, take it. If it is near the next dose time, then leave the thesis dose and determine your normal dose Do not double the dose to catch.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines under the toilet or drain them in the drain. When this period expires or is not required, leave this product appropriately. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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