Methyldopa Oral : Uses, Side Effects, Interactions



GENERIC NAME(S): Methyldopa


Methyldopa is used alone or with other medicines to treat hypertension. Reducing hypertension helps in preventing stroke, heart attack and kidney problems. Methyldopa works by relaxing the blood vessels so that the blood flows more easily.

How to use Methyldopa

Take Methyldopa with or without mouth directed by your doctor, usually 2 to 4 times daily. To reduce the risk of side effects, start this drug or evening increase in any new dose. Apart from this, if the dose of this drug is not equal, take a high dose while sleeping.

Dosage is based on your medical condition and treatment response.

Use Methyldopa regularly to get the most benefit. To help you remember, take it every day at the same time. It is important to continue taking this medicine even if you feel OK. Most people with high blood pressure do not feel sick.

When used for long periods of time, this medication can not work too and may require separate doses or additional medication. Talk to your doctor if this medicine stops working well (such as your blood pressure readings are high or increased).

Side Effects

Dizziness, nervousness, drowsiness, headache, stuffy nose, and weakness can be because your body gets adjusted in medicine. If any of these effects persists or worsens, tell your doctor or pharmacist immediately.

To reduce the risk of dizziness and lighthouse, slowly rise while sitting or lying down from the position of lying.

Remember that your doctor has prescribed Methyldopa because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

Immediately tell your doctor if you have any serious side effects, including: unconsciousness, muscle spasms / movements of uncontrolled muscles, missed / closed periods, sexual desire / decrease in capacity, breast size (in men), mental / Changes in mood (such as depression), symptoms of heart failure (such as shortness of breath, swelling of ankle / foot, abnormal fatigue, abnormal / sudden weight gain).

Methyldopa rarely causes a very serious (rarely fatal) liver disease or low red blood cell count (anemia). Tell your doctor immediately if you develop any symptoms of liver disease or anemia, including: abnormal fatigue, acute heartbeat, unexplained fever, dark urine, persistent nausea / vomiting, severe stomach / stomach ache, eyes or Yellowness of skin

A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.

In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or

In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.


Before taking Methyldopa, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.

Before using this drug, tell your doctor or pharmacist your medical history, especially: liver disease (such as hepatitis, cirrhosis), low red blood cell count (anemia), heart failure, pheochromocytoma, a certain genetic condition (Glucose-6-) deficiency of phosphate dehydrogenase).

Methyldopa may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or deaf. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Limit alcoholic beverages. If you are using marijuana, talk to your doctor.

Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially dizziness (standing for long), fainting or depression. Danger and dizziness can increase the risk of falling unconscious.

Tell your doctor if you are pregnant before using this medicine.

Methyldopa passes through breast milk but there is no possibility of harm to a nursing infant. Consult your doctor before breastfeeding.


Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription medicines and herbal products) and share it with your doctor and pharmacist. Do not start, stop or change any drug supplements without the approval of your doctor.

Some products that interact with this drug include: iron products (such as ferrous sulfate, ferrous gluconate), lithium.

Taking the MAO inhibitor with this drug can be a cause of serious (potentially fatal) drug interactions. During treatment with this drug, avoid taking the MAO inhibitor (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine). Most of the Mao blockers should not be taken for two weeks before treatment with this drug. Ask your doctor when to start or stop this medication.

Tell your doctor or pharmacist whether you are taking other products including alcohol, marijuana, antihistamines (such as cetirizinediphenhydramine), sleeping or anxiety medicines ((such as alprazolam, diazepam, zolpidem), muscle relaxants, and alcoholic painkillers Are. (Such as codeine).

Check the label on all your drugs (such as allergy or cough-and-cold products), because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Some products contain elements that can increase your blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough and cold products, diet aids, or NSAIDs such as ibuprofen / naproxen).

Methyldopa can interfere with some laboratory tests (including urine’s catecholamine  test), potentially incorrect examination results. Ensure that the lab staff and all your doctors know that you use this medicine.

Over Dose

If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness / dizziness.


Do not share this medication with others.

Labs and / or medical tests (such as hematocrit/hemoglobin, full blood count, Coombs test, liver function) should be periodically to monitor their progress or to examine side effects. Consult your doctor for more details.

Changes in lifestyle such as stress reduction programs, exercise and dietary changes can increase the effectiveness of this drug. Talk to your doctor or pharmacist about lifestyle changes that can benefit you.

Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure at home, and share the results with your doctor.

Missed Dose

If you miss a dose, then as soon as you remember, take it. If it is near the next dose time, then leave the thesis supplement and start your normal dose program again. Do not double the dose to catch up.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Until instructed to do so, do not flush the medicines in the toilet and do not drain them. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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