Dom-Domperidone – Uses, Side Effects, Interactions



Domperidone is a drug that enhances the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other medicines used for the treatment of Parkinson’s disease.

Domperidone is to be given only under the supervision of your doctor.

In deciding to use a drug, the risk of taking the medicine should be weighed against that good which he will. This is a decision that you and your doctor will make. For Domperidone, the following should be considered:


Tell your doctor if you have any unusual or allergic reaction to Domperidone or any other medication. Tell your health care professional if you have any other types of allergens, such as foods, dyes, preservatives or animals. For non-prescription products, read the label or package contents carefully.


Children – This medicine has been studied only in adult patients, and children of other age groups have no special information compared to the use of Domperidone.


Many medicines have not been studied especially in older people. Therefore, it can not be known whether they work in the same way as they do in older adults or if they cause various side effects or problems in old people. There is no specific information in comparison with the use of Domperidone in the elderly with use in other age groups.


During breastfeeding, there is no adequate study of women in determining infant risk while using this drug. Before taking Domperidone, weigh the potential benefit against potential risks before breastfeeding.

Drug Interactions

Although some medicines should not be used simultaneously, in other cases, two different medicines can be used simultaneously, even if a conversation can occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving Domperidone, it is especially important that your health care professional knows whether you are taking any of the medicines listed below. The following conversations have been selected based on their potential importance and not all are inclusive.

Domperidone is not used with any of the following medicines. Your doctor may decide not to treat this medicine or to replace some other medicines you may be taking.

•  Amifampridine
•  Amisulpride
•  Bepridil
•  Cisapride
•  Darunavir
•  Dronedarone
•  Fluconazole
•  ketoconazole
•  Mesoridazine
•  Pimozide
•  Piperaquine
•  Posaconazole
•  Saquinavir
•  Sparfloxacin
•  Terfenadine
•  Thioridazine
•  Ziprasidone

Using Domperidone with any of the following medicines is not generally recommended, but may be necessary in some cases. If both drugs are determined together, then your doctor may change the dose or how often you can use one or both medications.

•  Abiraterone
•  Alfuzosin
•  Alprazolam
•  Amiodarone
•  Amitriptyline
•  Amlodipine
•  Amoxapine
•  Amprenavir
•  Anagrelide
•  Apomorphine
•  Aprepitant
•  Aripiprazole
•  Aripeprazole loroxyl
•  Arsenic trioxide
•  Artemether
•  Asenapine
•  Astemizole
•  Atazanavir
•  Azithromycin
•  Bedaquiline
•  Bicalutamide
•  Boceprevir
•  Buprenorphine
•  Buserelin
•  Ceritinib
•  Chloroquine
•  Chlorpromazine
•  Cimetidine
•  Ciprofloxacin
•  Citalopram
•  Clarithromycin
•  Clomipramine
•  Clozapine
•  Cobicistat
•  Conivaptan
•  Crizotinib
•  Cyclobenzaprine
•  Cyclosporin
•  Dabrafenib
•  Dasatinib
•  Degarelix
•  Delamanid
•  Delavirdine
•  Desipramine
•  Deslorelin
•  Deutetrabenazine
•  Diltiazem
•  Disopyramide
•  Dofetilide
•  Dolasetron
•  Donepezil
•  Doxepin
•  Droperidol
•  Ebastine
•  Effervenges
•  Encorafenib
•  Eribulin
•  Erythromycin
•  Escitalopram
•  Famotidine
•  Felbamate
•  Fingolimod
•  Flecainide
•  Fluxotine
•  Fluxamine
•  Formoterol
•  Fosamprenavir
•  Fosaprepitant
•  Foscarnet
•  Fosnetupitant
•  Fosphenytoin
•  Galantamine
•  Gatifloxacin
•  Gemifloxacin
•  Ginkgo Biloba
•  Goldenseal
•  Gonadorelin
•  Gosselin
•  Granisetron
•  Halofantrine
•  Haloperidol
•  Histrelin
•  Hydroquinidine
•  Hydroxychloroquine
•  Hydroxyzine
•  Ibutilide
•  Idelalisib
•  Iloperidone
•  Imatinib
•  Imipramine
•  Indinavir
•  Inotuzumab Ozogamicin
•  Isoniazid
•  Itraconazole
•  Ivabradine
•  Ivosidenib
•  Lapatinib
•  Leoprolide
•  Levofloxacin
•  Lithium
•  Lofexidine
•  Lopinavir
•  Lumefantrine
•  Macimorelin
•  Mefloquine
•  Methadone
•  Metronidazole
•  Miconazole
•  Mifepristone
•  Mizolastine
•  Moxifloxacin
•  Nafarelin
•  Nefazodone
•  Nelfinavir
•  Netupitant
•  Nilotinib
•  Norfloxacin
•  Nortripetine
•  Octreotide
•  Offloxacin
•  Ondansetron
•  Osimertinib
•  Paliperidone
•  Panobinostat
•  Paroxetine
•  Pasireotide
•  Pazopanib
•  Pentamidine
•  Perphenazine
•  Pimavanserin
•  Pipamperone
•  Pitolisant
•  Probucol
•  Procainamide
•  Prochlorperazine
•  Promethazine
•  Propafenone
•  Protriptyline
•  Quetiapine
•  Quinidine
• Quinine
•  Rhenitidin
•  Ranolazine
•  Ribociclib
•  Rilpivirine
•  Risperidone
•  Ritonavir
•  Salmeterol
•  Selegiline
•  Sirtindole
•  Sertline
•  Sevoflurane
•  Sodium phosphate
•  Sodium phosphate, digic
•  Sodium phosphate, monohasic
•  Solifenacin
•  Sorafenib
•  Sothool
•  Sulpiride
•  Sunitinib
•  Tacrolimus
•  Tamoxifen
•  Telaprevir
•  Telavancin
•  Telithromycin
•  Tetrabenazine
•  Ticagrelor
•  Tizanidine
•  Tolterodine
•  Toremifene
•  Trazodone
•  Trifluoperazine
•  Trimipramine
•  Triptorelin
•  Vandetanib
•  Vardenafil
•  Vemurafenib
•  Venlafaxine
•  Verapamil
•  Vinflunine
•  Voriconazole
•  Vorinostat
•  Zuclopenthixol

Other Interactions

Some medicines should not be used at the time of eating or around or there may be talks after eating certain types of food. Alcohol or tobacco use may also be negotiated with some medicines. The following conversations have been selected based on their potential importance and not all are inclusive.

Using this drug with any of the following is not generally recommended, but in some cases it may be indispensable. If used together, your doctor may change the dose or how often you can use this medicine, or give special instructions about the use of food, alcohol or tobacco.

•  Grape juice

Other Medical Problems

The presence of other medical problems can affect the use of this drug. Make sure you tell your doctor if you have any other medical problem, especially:

•  Bleeding or other bowel problems
•  Pituitary (brain) tumors
•  Liver disease
•  Medication susceptibility to Domperidone


This drug dose will be different for different patients. Follow the instructions given on your doctor’s order or label. The following information only includes the average dose of this drug. If your dosage is different, do not change it until your doctor tells you to do this.

The amount of medication you take depends on the strength of the drug. In addition, the dosage you take each day, time is allowed between dose, and the time you take medication depends on the medical problem for which you are using the medicine.

Form for oral dosage (tablets):
•  Treatment of Gastrointestinal Disorders:
Adult – Daily 10 mg (mg) three to four times daily Some patients may require high doses of up to 20 mg of three or four times per day.
•  Nausea and vomiting:
Adult – daily 20 mg (mg) three to four times daily

Missed Dose

If you miss a dose of this medicine, then take it as soon as possible. However, if this is almost time for your next dose, leave the missed dose and go back to your regular diet program. Do not take double dose.


Store the medicine in a closed container at room temperature, away from heat, moisture and direct light. Avoid cold.

Keep away from children’s access.

Do not require old medicine.

Precautions of Domperidone

It is very important that your doctor check your progress on regular visits. This will allow your doctor to see if the drug is working properly and to decide whether you should continue taking it.

If your symptoms do not improve within a few days or if they get worse, then check with your doctor.

Side Effects of Domperidone

With its necessary effects, a drug can cause some undesirable effects. Although these side effects can not occur, if they are, they may need medical attention.

Symptoms of overdose
•  Difficulty speaking
•  Disorientation
•  Dizziness
•  Unconsciousness
•  Irregular heart beat
•  Light-headedness
•  Balance or loss of muscle control

Immediately check with your doctor if any of the following have any side effects:

Less Prevalent

•  Balance or loss of muscle control
•  Swelling of the mouth
•  Fast, irregular, fast, or heartbeat or pulse race
•  Swelling in the face, hands, lower legs or legs

There may be some side effects that do not usually require medical attention. These side effects can be overcome during treatment because your body gets adjusted with medication. In addition, your health care professional may be able to tell you about these ways to prevent or reduce some of these side effects. Check with your health care professional that any of the following side effects are ongoing or upset or if you have any questions about them:

Less Prevalent
•  Nipple breast milk
•  Dry mouth
•  Breast Swelling in Men
•  Head ache
•  Hives
•  Hot flashes
•  Skin Itching
•  Itching, redness, pain, or swelling of the eye
•  Menstrual irregularity
•  Pain in the breast

•  Changes in the need to urinate
•  Change in appetite
•  Constipation
•  Diarrhea
•  Burning, difficult or painful urination
•  Difficulty speaking
•  Dizziness
•  Sleepiness
•  Heartburn
•  Irritability
•  Power deficit or loss
•  Leg cramps
•  Mental retardation
•  Nervousness
•  Beating
•  Slow down
•  Abdominal cramps
•  Thirst
•  Fatigue
•  Weakness

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